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CLEC5A: A Promiscuous Pattern Recognition Receptor to Microbes and Beyond

CLEC5A is a spleen tyrosine kinase (Syk)-coupled C-type lectin that is highly expressed by monocytes, macrophages, neutrophils, and dendritic cells and interacts with virions directly, via terminal fucose and mannose moieties of viral glycans. CLEC5A also binds to N-acetylglucosamine (GlcNAc) and N-...

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Bibliografiske detaljer
Udgivet i:Lectin in Host Defense Against Microbial Infections
Main Authors: Sung, Pei-Shan, Chang, Wei-Chiao, Hsieh, Shie-Liang
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7121389/
https://ncbi.nlm.nih.gov/pubmed/32152943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-981-15-1580-4_3
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