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CLEC5A: A Promiscuous Pattern Recognition Receptor to Microbes and Beyond
CLEC5A is a spleen tyrosine kinase (Syk)-coupled C-type lectin that is highly expressed by monocytes, macrophages, neutrophils, and dendritic cells and interacts with virions directly, via terminal fucose and mannose moieties of viral glycans. CLEC5A also binds to N-acetylglucosamine (GlcNAc) and N-...
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| Udgivet i: | Lectin in Host Defense Against Microbial Infections |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7121389/ https://ncbi.nlm.nih.gov/pubmed/32152943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-981-15-1580-4_3 |
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