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CLEC5A: A Promiscuous Pattern Recognition Receptor to Microbes and Beyond
CLEC5A is a spleen tyrosine kinase (Syk)-coupled C-type lectin that is highly expressed by monocytes, macrophages, neutrophils, and dendritic cells and interacts with virions directly, via terminal fucose and mannose moieties of viral glycans. CLEC5A also binds to N-acetylglucosamine (GlcNAc) and N-...
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| Publicado no: | Lectin in Host Defense Against Microbial Infections |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7121389/ https://ncbi.nlm.nih.gov/pubmed/32152943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-981-15-1580-4_3 |
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