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Somatic synonymous mutations in regulatory elements contribute to the genetic aetiology of melanoma

BACKGROUND: Non-synonymous mutations altering tumor suppressor genes and oncogenes are widely studied. However, synonymous mutations, which do not alter the protein sequence, are rarely investigated in melanoma genome studies. METHODS: We explored the role of somatic synonymous mutations in melanoma...

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Detaylı Bibliyografya
Yayımlandı:BMC Med Genomics
Asıl Yazarlar: Zhang, Di, Xia, Junfeng
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2020
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7119296/
https://ncbi.nlm.nih.gov/pubmed/32241263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-020-0685-2
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