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Recognizing and stabilizing miR-21 by chiral ruthenium(II) complexes

MiR-21, a non-coding miRNA with 22 nucleotides, plays an important part in the proliferation, invasion, and metastasis of tumor cells. The present study demonstrates that isomers of chiral ruthenium(II) complexes with alkynes (Λ-1 and Δ-1) were synthesized by Songogashira coupling reaction by using...

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Detalhes bibliográficos
Publicado no:BMC Chem
Main Authors: Feng, Yin, Shu, Jing, Yao, Liangzhong, Lan, Yutao, Ye, Lianbao, Mei, Wenjie, Ding, Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7119291/
https://ncbi.nlm.nih.gov/pubmed/32266333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-020-00672-8
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