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miR-21 and miR-31 Converge on TIAM1 to Regulate Migration and Invasion of Colon Carcinoma Cells

TGF-β promotes cell migration and invasion, an attribute that is linked to the pro-metastasis function of this cytokine in late stage cancers. The LIM 1863 colon carcinoma organoid undergoes epithelial-mesenchymal transition (EMT) in response to TGF-β. This process is markedly accelerated by TNF-α,...

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Main Authors: Cottonham, Charisa L., Kaneko, Satoshi, Xu, Lan
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975153/
https://ncbi.nlm.nih.gov/pubmed/20826792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.160069
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