miR-21 and miR-145 cooperation in regulation of colon cancer stem cells

BACKGROUND: Acquired drug resistance is one of the major reasons for failing cancer therapies. Although the reasons are not fully understood, they may be related to the presence of cancer stem cells (CSCs). We have reported that chemo-resistant (CR) colon cancer cells, highly enriched in CSCs, exhib...

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Bibliographic Details
Published in:Mol Cancer
Main Authors: Yu, Yingjie, Nangia-Makker, Pratima, Farhana, Lulu, G. Rajendra, Sindhu, Levi, Edi, Majumdar, Adhip PN
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415383/
https://ncbi.nlm.nih.gov/pubmed/25928322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0372-7
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