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miR-21 and miR-145 cooperation in regulation of colon cancer stem cells

BACKGROUND: Acquired drug resistance is one of the major reasons for failing cancer therapies. Although the reasons are not fully understood, they may be related to the presence of cancer stem cells (CSCs). We have reported that chemo-resistant (CR) colon cancer cells, highly enriched in CSCs, exhib...

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Detalles Bibliográficos
Publicado en:Mol Cancer
Main Authors: Yu, Yingjie, Nangia-Makker, Pratima, Farhana, Lulu, G. Rajendra, Sindhu, Levi, Edi, Majumdar, Adhip PN
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415383/
https://ncbi.nlm.nih.gov/pubmed/25928322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0372-7
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