The Mechanics of Translocation: A Molecular “Spring-and-Ratchet” System

The translation of genetic information into proteins is a fundamental process of life. Stepwise addition of amino acids to the growing polypeptide chain requires the coordinated movement of mRNA and tRNAs through the ribosome, a process known as translocation. Here, we review current understanding o...

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Udgivet i:Structure
Main Authors: Moran, Stephen J., Flanagan, John F., Namy, Olivier, Stuart, David I., Brierley, Ian, Gilbert, Robert J.C.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Ltd. 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7119126/
https://ncbi.nlm.nih.gov/pubmed/18462671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.04.001
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