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Co-localization between Sequence Constraint and Epigenomic Information Improves Interpretation of Whole-Genome Sequencing Data
The identification of functional regions in the noncoding human genome is difficult but critical in order to gain understanding of the role noncoding variation plays in gene regulation in human health and disease. We describe here a co-localization approach that aims to identify constrained sequence...
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| 發表在: | Am J Hum Genet |
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| Main Authors: | , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7118583/ https://ncbi.nlm.nih.gov/pubmed/32243819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2020.03.003 |
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