Modulating the Distant Spreading of Patient-Derived Colorectal Cancer Cells via Aspirin and Metformin

Although screening has reduced mortality rates for colorectal cancer (CRC), about 20% of patients still carry metastases at diagnosis. Postsurgery chemotherapy is toxic and induces drug resistance. Promising alternative strategies rely on repurposing drugs such as aspirin (ASA) and metformin (MET)....

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Bibliografiske detaljer
Udgivet i:Transl Oncol
Main Authors: Palazzolo, Gemma, Mollica, Hilaria, Lusi, Valeria, Rutigliani, Mariangela, Di Francesco, Martina, Pereira, Rui Cruz, Filauro, Marco, Paleari, Laura, DeCensi, Andrea, Decuzzi, Paolo
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press 2020
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Original article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118176/
https://ncbi.nlm.nih.gov/pubmed/32247264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100760
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