Deciphering the relative contribution of vascular inflammation and blood rheology in metastatic spreading

Vascular adhesion of circulating tumor cells (CTCs) is a key step in cancer spreading. If inflammation is recognized to favor the formation of vascular “metastatic niches,” little is known about the contribution of blood rheology to CTC deposition. Herein, a microfluidic chip, covered by a confluent...

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Veröffentlicht in:Biomicrofluidics
Hauptverfasser: Mollica, Hilaria, Coclite, Alessandro, Miali, Marco E., Pereira, Rui C., Paleari, Laura, Manneschi, Chiara, DeCensi, Andrea, Decuzzi, Paolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: AIP Publishing LLC 2018
Schlagworte:
SPECIAL TOPIC: BIO-TRANSPORT PROCESSES AND DRUG DELIVERY IN PHYSIOLOGICAL MICRO-DEVICES
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5957635/
https://ncbi.nlm.nih.gov/pubmed/29861816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.5022879
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