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The yin and yang of co-inhibitory receptors: toward anti-tumor immunity without autoimmunity
Co-inhibitory receptors are important regulators of T-cell function that define the balance between tolerance and autoimmunity. The immune regulatory function of co-inhibitory receptors, including CTLA-4, PD-1, TIM-3, TIGIT, and LAG-3, was first discovered in the setting of autoimmune disease models...
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| Publicado no: | Cell Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Singapore
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7118128/ https://ncbi.nlm.nih.gov/pubmed/31974523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41422-020-0277-x |
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