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The Yin and Yang of Interleukin-21 in Allergy, Autoimmunity and Cancer
IL-21 is a type I cytokine that like IL-2, IL-4, IL-7, IL-9, and IL-15 shares the common cytokine receptor γ chain, γ(c). IL-21 is produced by activated CD4(+) T cells, NKT cells, and Th17 cells, and has pleiotropic actions on a range of lymphoid lineages. IL-21 regulates immunoglobulin production a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2546604/ https://ncbi.nlm.nih.gov/pubmed/18554883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2008.02.004 |
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