ASK1 inhibits browning of white adipose tissue in obesity

Increasing energy expenditure via induction of adipose tissue browning has become an appealing strategy to treat obesity and associated metabolic complications. Herein, we identify adipocyte-expressed apoptosis signal-regulating kinase 1 (ASK1) as regulator of adipose tissue browning. High fat diet-...

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Publicado no:Nat Commun
Main Authors: Lucchini, Fabrizio C., Wueest, Stephan, Challa, Tenagne D., Item, Flurin, Modica, Salvatore, Borsigova, Marcela, Haim, Yulia, Wolfrum, Christian, Rudich, Assaf, Konrad, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118089/
https://ncbi.nlm.nih.gov/pubmed/32242025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15483-7
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