ASK1 inhibits browning of white adipose tissue in obesity

Increasing energy expenditure via induction of adipose tissue browning has become an appealing strategy to treat obesity and associated metabolic complications. Herein, we identify adipocyte-expressed apoptosis signal-regulating kinase 1 (ASK1) as regulator of adipose tissue browning. High fat diet-...

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發表在:Nat Commun
Main Authors: Lucchini, Fabrizio C., Wueest, Stephan, Challa, Tenagne D., Item, Flurin, Modica, Salvatore, Borsigova, Marcela, Haim, Yulia, Wolfrum, Christian, Rudich, Assaf, Konrad, Daniel
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7118089/
https://ncbi.nlm.nih.gov/pubmed/32242025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15483-7
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