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The Caenorhabditis elegans homolog of the Evi1 proto-oncogene, egl-43, coordinates G1 cell cycle arrest with pro-invasive gene expression during anchor cell invasion

Cell invasion allows cells to migrate across compartment boundaries formed by basement membranes. Aberrant cell invasion is a first step during the formation of metastases by malignant cancer cells. Anchor cell (AC) invasion in C. elegans is an excellent in vivo model to study the regulation of cell...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Deng, Ting, Stempor, Przemyslaw, Appert, Alex, Daube, Michael, Ahringer, Julie, Hajnal, Alex, Lattmann, Evelyn
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7117773/
https://ncbi.nlm.nih.gov/pubmed/32203506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008470
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