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Barcoded DNA origami structures for multiplexed optimization and enrichment of DNA-based protein-binding cavities
Simultaneous binding of molecules by multiple binding partners is known to strongly reduce the apparent dissociation constant of the corresponding molecular complexes and can be used to realize strong, non-covalent molecular interactions. Based on this principle, efficient binding of proteins to DNA...
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| Publicado en: | Nat Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116572/ https://ncbi.nlm.nih.gov/pubmed/32661410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41557-020-0504-6 |
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