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DNA Origami Seesaws as Comparative Binding Assay

The application of commonly used force spectroscopy in biological systems is often limited by the need for an invasive tether connecting the molecules of interest to a bead or cantilever tip. Here we present a DNA origami‐based prototype in a comparative binding assay. It has the advantage of in sit...

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Bibliographic Details
Published in:Chembiochem
Main Authors: Nickels, Philipp C., Høiberg, Hans C., Simmel, Stephanie S., Holzmeister, Phil, Tinnefeld, Philip, Liedl, Tim
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5084756/
https://ncbi.nlm.nih.gov/pubmed/27038073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201600059
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