Downregulation of 15-hydroxyprostaglandin dehydrogenase during acquired tamoxifen resistance and association with poor prognosis in ERα-positive breast cancer

AIM: Tamoxifen (TAM) resistance remains a clinical issue in breast cancer. The authors previously reported that 15-hydroxyprostaglandin dehydrogenase (HPGD) was significantly downregulated in tamoxifen-resistant (TAMr) breast cancer cell lines. Here, the authors investigated the relationship between...

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Vydáno v:Explor Target Antitumor Ther
Hlavní autoři: Volpato, Milene, Cummings, Michele, Shaaban, Abeer M., Abderrahman, Balkees, Hull, Mark A., Maximov, Philipp Y., Broom, Bradley M., Hoppe, Reiner, Fan, Ping, Brauch, Hiltrud, Jordan, V. Craig, Speirs, Valerie
Médium: Artigo
Jazyk:Inglês
Vydáno: Open Exploration 2020
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116369/
https://ncbi.nlm.nih.gov/pubmed/33210098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.37349/etat.2020.00021
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