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Mitochondrial Dysfunction Accelerates Ageing

We review here the seminal findings of Desdin-Mico et al. showing that T cells with dysfunctional mitochondria induce multimorbity and premature senescence, due to mitochondrial transcription factor A (TFAM). They add further weight to the idea that targeting immunometabolism could be beneficial in...

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Bibliografiske detaljer
Udgivet i:Immunometabolism
Main Authors: Schroth, Johannes, Henson, Sian M.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116259/
https://ncbi.nlm.nih.gov/pubmed/33101729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20900/immunometab20200035
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