Hypoxia-induced TGF-β–RBFOX2–ESRP1 axis regulates human MENA alternative splicing and promotes EMT in breast cancer

Hypoxic microenvironment heralds epithelial–mesenchymal transition (EMT), invasion and metastasis in solid tumors. Deregulation of alternative splicing (AS) of several cancer-associated genes has been instrumental in hypoxia-induced EMT. Our study in breast cancer unveils a previously unreported mec...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:NAR Cancer
Prif Awduron: Ahuja, Neha, Ashok, Cheemala, Natua, Subhashis, Pant, Deepak, Cherian, Anna, Pandkar, Madhura R, Yadav, Pooja, Narayanan S.S., Vishnu, Mishra, Jharna, Samaiya, Atul, Shukla, Sanjeev
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Cancer-specific RNAs and RNA Processing
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116222/
https://ncbi.nlm.nih.gov/pubmed/33089214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcaa021
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