Attenuation of highly pathogenic porcine reproductive and respiratory syndrome virus by inserting an additional transcription unit

Transcription regulatory sequences (TRSs) play a key role in the synthesis of porcine reproductive and respiratory syndrome virus (PRRSV) subgenomic mRNAs, which resembles similarity-assisted RNA recombination. In this study, genome instability was found when a highly pathogenic PRRSV (HP-PRRSV) str...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Wang, Lianghai, Hou, Jun, Gao, Li, Guo, Xue-kun, Yu, Zhibin, Zhu, Yaohua, Liu, Yihao, Tang, Jun, Zhang, Hexiao, Feng, Wen-hai
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115595/
https://ncbi.nlm.nih.gov/pubmed/25171845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.08.036
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