Induction of interleukin-10 is dependent on p38 mitogen-activated protein kinase pathway in macrophages infected with porcine reproductive and respiratory syndrome virus

BACKGROUND: Porcine reproductive and respiratory syndrome virus (PRRSV) causes reproductive failure and respiratory illness in pigs and usually establishes a persistent infection. Previous studies suggested that interleukin-10 (IL-10) could play a critical role in PRRSV-induced immunosuppression. Ho...

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Detalhes bibliográficos
Main Authors: Hou, Jun, Wang, Lianghai, Quan, Rong, Fu, Yi, Zhang, Hexiao, Feng, Wen-hai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441385/
https://ncbi.nlm.nih.gov/pubmed/22909062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-9-165
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