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rOv-ASP-1, a recombinant secreted protein of the helminth Onchocercavolvulus, is a potent adjuvant for inducing antibodies to ovalbumin, HIV-1 polypeptide and SARS-CoV peptide antigens

We studied the adjuvanticity of recombinant Onchocerca volvulus activation associated protein-1 (rOv-ASP-1) for ovalbumin (OVA) in mice. After a single immunization and one boost, rOv-ASP-1 exceeded the efficacy of alum or MPL + TDM adjuvants in terms of end-point total IgG or IgG1 and IgG2a anti-OV...

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Dades bibliogràfiques
Publicat a:Vaccine
Autors principals: MacDonald, Angus J., Cao, Long, He, Yuxian, Zhao, Qian, Jiang, Shibo, Lustigman, Sara
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Ltd. 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115491/
https://ncbi.nlm.nih.gov/pubmed/15837368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2005.01.098
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