Nasal delivery of Protollin-adjuvanted H5N1 vaccine induces enhanced systemic as well as mucosal immunity in mice

Sporadic, yet frequent human infections with avian H5N1 influenza A viruses continue to pose a potential pandemic threat. Poor immunogenicity of unadjuvanted H5N1 vaccines warrants developing novel adjuvants and formulations as well as alternate delivery systems to improve their immunogenicity and e...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Cao, Weiping, Kim, Jin Hyang, Reber, Adrian J., Hoelscher, Mary, Belser, Jessica A., Lu, Xiuhua, Katz, Jacqueline M., Gangappa, Shivaprakash, Plante, Martin, Burt, David S., Sambhara, Suryaprakash
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Elsevier Ltd. 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115484/
https://ncbi.nlm.nih.gov/pubmed/28499553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.05.004
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