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Prevalence of serum neutralizing antibodies to adenovirus type 5 (Ad5) and 41 (Ad41) in children is associated with age and sanitary conditions

Neutralizing antibody (NAb) can dampen the immunogenicity of adenovirus (Ad) vector-based vaccine. Vector systems based on human adenovirus type 41 (Ad41) have been constructed and used to develop recombinant vaccines. Here, we attempted to study the seroprevalence of NAbs to Ad5 and Ad41 among chil...

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Podrobná bibliografie
Vydáno v:Vaccine
Hlavní autoři: Yang, Wei-Xiong, Zou, Xiao-Hui, Jiang, Shuang-Ying, Lu, Nan-Nan, Han, Mei, Zhao, Jian-Hai, Guo, Xiao-Juan, Zhao, Sheng-Cang, Lu, Zhuo-Zhuang
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier Ltd. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115419/
https://ncbi.nlm.nih.gov/pubmed/27682509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.09.043
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