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Effect of synaptic cell-to-cell transmission and recombination on the evolution of double mutants in HIV

Recombination in HIV infection can impact virus evolution in vivo in complex ways, as has been shown both experimentally and mathematically. The effect of free virus versus synaptic, cell-to-cell transmission on the evolution of double mutants, however, has not been investigated. Here, we do so by u...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J R Soc Interface
Main Authors: Kreger, Jesse, Komarova, Natalia L., Wodarz, Dominik
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115232/
https://ncbi.nlm.nih.gov/pubmed/32208824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2019.0832
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