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Effect of synaptic cell-to-cell transmission and recombination on the evolution of double mutants in HIV

Recombination in HIV infection can impact virus evolution in vivo in complex ways, as has been shown both experimentally and mathematically. The effect of free virus versus synaptic, cell-to-cell transmission on the evolution of double mutants, however, has not been investigated. Here, we do so by u...

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Vydáno v:J R Soc Interface
Hlavní autoři: Kreger, Jesse, Komarova, Natalia L., Wodarz, Dominik
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115232/
https://ncbi.nlm.nih.gov/pubmed/32208824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2019.0832
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