Noncanonical Roles of hα-syn (A53T) in the Pathogenesis of Parkinson's Disease: Synaptic Pathology and Neuronal Aging

The motor and nonmotor symptoms of PD involve several brain regions. However, whether α-syn pathology originating from the SNc can directly lead to the pathological changes in distant cerebral regions and induce PD-related symptoms remains unclear. Here, AAV9-synapsin-mCherry-human SNCA (A53T) was i...

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Detalhes bibliográficos
Publicado no:Neural Plast
Main Authors: Wang, Qing-Jun, Chen, An-Di, Chen, Hai-Chao, Wang, Dong-Xin, Cai, Yi-Ting, Yin, Jie, Jing, Yu-Hong, Gao, Li-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115172/
https://ncbi.nlm.nih.gov/pubmed/32273890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/6283754
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