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A Strategic Target Rescues Trimethoprim Sensitivity in Escherichia coli
Trimethoprim, a preferred treatment for urinary tract infections, is becoming obsolete owing to the rapid dissemination of resistant E. coli. Although direct resistance mechanisms such as overexpression of a mutant FolA and dfr enzymes are well characterized, associated alterations that drive or sus...
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| Veröffentlicht in: | iScience |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7115098/ https://ncbi.nlm.nih.gov/pubmed/32240953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100986 |
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