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A Strategic Target Rescues Trimethoprim Sensitivity in Escherichia coli
Trimethoprim, a preferred treatment for urinary tract infections, is becoming obsolete owing to the rapid dissemination of resistant E. coli. Although direct resistance mechanisms such as overexpression of a mutant FolA and dfr enzymes are well characterized, associated alterations that drive or sus...
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| 發表在: | iScience |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7115098/ https://ncbi.nlm.nih.gov/pubmed/32240953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.100986 |
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