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The SARS coronavirus spike glycoprotein is selectively recognized by lung surfactant protein D and activates macrophages

The severe acute respiratory syndrome coronavirus (SARS-CoV) infects host cells with its surface glycosylated spike-protein (S-protein). Here we expressed the SARS-CoV S-protein to investigate its interactions with innate immune mechanisms in the lung. The purified S-protein was detected as a 210 kD...

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Podrobná bibliografie
Vydáno v:Immunobiology
Hlavní autoři: Leth-Larsen, Rikke, Zhong, Fei, Chow, Vincent T.K., Holmskov, Uffe, Lu, Jinhua
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier GmbH. 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114820/
https://ncbi.nlm.nih.gov/pubmed/17412287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2006.12.001
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