A hallmark of phospholamban functional divergence is located in the N-terminal phosphorylation domain

Sarcoplasmic reticulum Ca(2+) pump (SERCA) is a critical component of the Ca(2+) transport machinery in myocytes. There is clear evidence for regulation of SERCA activity by PLB, whose activity is modulated by phosphorylation of its N-terminal domain (residues 1–25), but there is less clear evidence...

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Опубликовано в: :Comput Struct Biotechnol J
Главные авторы: Fernández-de Gortari, Eli, Aguayo-Ortiz, Rodrigo, Autry, Joseph M., Michel Espinoza-Fonseca, L.
Формат: Artigo
Язык:Inglês
Опубликовано: Research Network of Computational and Structural Biotechnology 2020
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114604/
https://ncbi.nlm.nih.gov/pubmed/32257054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2020.02.016
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