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Effects of hypervariable regions in spike protein on pathogenicity, tropism, and serotypes of infectious bronchitis virus
To study the roles of hypervariable regions (HVRs) in receptor-binding subunit S1 of the spike protein, we manipulated the genome of the IBV Beaudette strain using a reverse genetics system to construct seven recombinant strains by separately or simultaneously replacing the three HVRs of the Beaudet...
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| Pubblicato in: | Virus Res |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier B.V.
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7114591/ https://ncbi.nlm.nih.gov/pubmed/29684409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2018.04.013 |
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