In vivo growth of porcine reproductive and respiratory syndrome virus engineered nsp2 deletion mutants

Prior studies on PRRSV strain VR-2332 non-structural protein 2 (nsp2) had shown that as much as 403 amino acids could be removed from the hypervariable region without losing virus viability in vitro. We utilized selected nsp2 deletion mutants to examine in vivo growth. Young swine (4 pigs/group; 5 c...

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Bibliographische Detailangaben
Veröffentlicht in:Virus Res
Hauptverfasser: Faaberg, Kay S., Kehrli, Marcus E., Lager, Kelly M., Guo, Baoqing, Han, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier Science 2010
Schlagworte:
Review
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114397/
https://ncbi.nlm.nih.gov/pubmed/20673840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2010.07.024
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