The Porcine Reproductive and Respiratory Syndrome Virus nsp2 Cysteine Protease Domain Possesses both trans- and cis-Cleavage Activities

The N terminus of the replicase nonstructural protein 2 (nsp2) of porcine reproductive and respiratory syndrome virus (PRRSV) contains a putative cysteine protease domain (PL2). Previously, we demonstrated that deletion of either the PL2 core domain (amino acids [aa] 47 to 180) or the immediate down...

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Detaylı Bibliyografya
Asıl Yazarlar: Han, Jun, Rutherford, Mark S., Faaberg, Kay S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2009
Konular:
Genome Replication and Regulation of Viral Gene Expression
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738230/
https://ncbi.nlm.nih.gov/pubmed/19587037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00834-09
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