Cellular protein GLTSCR2: A valuable target for the development of broad-spectrum antivirals

Viral infection induces translocation of the nucleolar protein GLTSCR2 from the nucleus to the cytoplasm, resulting in attenuation of the type I interferon IFN-β. Addressing the role of GLTSCR2 in viral replication, we detect that knocking down GLTSCR2 by shRNAs results in significant suppression of...

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Pubblicato in:Antiviral Res
Autori principali: Li, Cui-Cui, Dong, Hui-Jun, Wang, Peng, Meng, Wen, Chi, Xiao-Jing, Han, Shi-Chong, Ning, Shuo, Wang, Chuang, Wang, Xiao-Jia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier B.V. 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113796/
https://ncbi.nlm.nih.gov/pubmed/28286234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2017.03.004
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