Human DDX3 protein is a valuable target to develop broad spectrum antiviral agents

Targeting a host factor essential for the replication of different viruses but not for the cells offers a higher genetic barrier to the development of resistance, may simplify therapy regimens for coinfections, and facilitates management of emerging viral diseases. DEAD-box polypeptide 3 (DDX3) is a...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Brai, Annalaura, Fazi, Roberta, Tintori, Cristina, Zamperini, Claudio, Bugli, Francesca, Sanguinetti, Maurizio, Stigliano, Egidio, Esté, José, Badia, Roger, Franco, Sandra, Martinez, Miguel A., Martinez, Javier P., Meyerhans, Andreas, Saladini, Francesco, Zazzi, Maurizio, Garbelli, Anna, Maga, Giovanni, Botta, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4868442/
https://ncbi.nlm.nih.gov/pubmed/27118832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522987113
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