Rapamycin-induced autophagy restricts porcine epidemic diarrhea virus infectivity in porcine intestinal epithelial cells

Porcine epidemic diarrhea virus (PEDV) invades porcine intestinal epithelial cells (IECs) and causes diarrhea and dehydration in pigs. In the present study, we showed a suppression of PEDV infection in porcine jejunum intestinal epithelial cells (IPEC-J2) by an increase in autophagy. Autophagy was a...

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Publicado en:Antiviral Res
Autores principales: Ko, Seongyeol, Gu, Min Jeong, Kim, Cheol Gyun, Kye, Yoon Chul, Lim, Younggap, Lee, Ji Eun, Park, Byung-Chul, Chu, Hyuk, Han, Seung Hyun, Yun, Cheol-Heui
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier B.V. 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113733/
https://ncbi.nlm.nih.gov/pubmed/28842266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2017.08.010
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