Rapamycin-induced autophagy restricts porcine epidemic diarrhea virus infectivity in porcine intestinal epithelial cells

Porcine epidemic diarrhea virus (PEDV) invades porcine intestinal epithelial cells (IECs) and causes diarrhea and dehydration in pigs. In the present study, we showed a suppression of PEDV infection in porcine jejunum intestinal epithelial cells (IPEC-J2) by an increase in autophagy. Autophagy was a...

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Bibliographic Details
Published in:Antiviral Res
Main Authors: Ko, Seongyeol, Gu, Min Jeong, Kim, Cheol Gyun, Kye, Yoon Chul, Lim, Younggap, Lee, Ji Eun, Park, Byung-Chul, Chu, Hyuk, Han, Seung Hyun, Yun, Cheol-Heui
Format: Artigo
Language:Inglês
Published: Elsevier B.V. 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113733/
https://ncbi.nlm.nih.gov/pubmed/28842266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2017.08.010
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