MACROD2 deficiency promotes hepatocellular carcinoma growth and metastasis by activating GSK-3β/β-catenin signaling

Structural variations (SVs) influence the development and progression of multiple types of cancer. The genes affected by SVs in hepatocellular carcinoma (HCC) and their contribution to tumor growth and metastasis remain unknown. In this study, through whole-genome sequencing (WGS), we identified MAC...

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Detalhes bibliográficos
Publicado no:NPJ Genom Med
Main Authors: Zhou, Zheng-Jun, Luo, Chu-Bin, Xin, Hao-Yang, Hu, Zhi-Qiang, Zhu, Gui-Qi, Li, Jia, Zhou, Shao-Lai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113304/
https://ncbi.nlm.nih.gov/pubmed/32257385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-020-0122-7
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