MACROD2 deficiency promotes hepatocellular carcinoma growth and metastasis by activating GSK-3β/β-catenin signaling

Structural variations (SVs) influence the development and progression of multiple types of cancer. The genes affected by SVs in hepatocellular carcinoma (HCC) and their contribution to tumor growth and metastasis remain unknown. In this study, through whole-genome sequencing (WGS), we identified MAC...

Full description

Saved in:
Bibliographic Details
Published in:NPJ Genom Med
Main Authors: Zhou, Zheng-Jun, Luo, Chu-Bin, Xin, Hao-Yang, Hu, Zhi-Qiang, Zhu, Gui-Qi, Li, Jia, Zhou, Shao-Lai
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2020
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113304/
https://ncbi.nlm.nih.gov/pubmed/32257385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41525-020-0122-7
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items