Generation of novel affibody molecules targeting the EBV LMP2A N-terminal domain with inhibiting effects on the proliferation of nasopharyngeal carcinoma cells

Nasopharyngeal carcinoma (NPC) induced by latent infection with Epstein-Barr virus (EBV) remains the most common head and neck cancer in Southeast Asia, especially in the southern part of China. It is well known that persistent expression of two EBV latent membrane proteins (LMP1/LMP2A) plays a key...

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Vydáno v:Cell Death Dis
Hlavní autoři: Zhu, Jinshun, Kamara, Saidu, Cen, Danwei, Tang, Wanlin, Gu, Meiping, Ci, Xingyuan, Chen, Jun, Wang, Lude, Zhu, Shanli, Jiang, Pengfei, Chen, Shao, Xue, Xiangyang, Zhang, Lifang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113277/
https://ncbi.nlm.nih.gov/pubmed/32238802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2410-7
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