Generation of novel affibody molecules targeting the EBV LMP2A N-terminal domain with inhibiting effects on the proliferation of nasopharyngeal carcinoma cells

Nasopharyngeal carcinoma (NPC) induced by latent infection with Epstein-Barr virus (EBV) remains the most common head and neck cancer in Southeast Asia, especially in the southern part of China. It is well known that persistent expression of two EBV latent membrane proteins (LMP1/LMP2A) plays a key...

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Veröffentlicht in:Cell Death Dis
Hauptverfasser: Zhu, Jinshun, Kamara, Saidu, Cen, Danwei, Tang, Wanlin, Gu, Meiping, Ci, Xingyuan, Chen, Jun, Wang, Lude, Zhu, Shanli, Jiang, Pengfei, Chen, Shao, Xue, Xiangyang, Zhang, Lifang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113277/
https://ncbi.nlm.nih.gov/pubmed/32238802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2410-7
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