Knockdown of Foxg1 in supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse cochlea

Foxg1 is one of the forkhead box genes that are involved in morphogenesis, cell fate determination, and proliferation, and Foxg1 was previously reported to be required for morphogenesis of the mammalian inner ear. However, Foxg1 knock-out mice die at birth, and thus the role of Foxg1 in regulating h...

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Publié dans:Cell Mol Life Sci
Auteurs principaux: Zhang, Shasha, Zhang, Yuan, Dong, Ying, Guo, Lingna, Zhang, Zhong, Shao, Buwei, Qi, Jieyu, Zhou, Han, Zhu, Weijie, Yan, Xiaoqian, Hong, Guodong, Zhang, Liyan, Zhang, Xiaoli, Tang, Mingliang, Zhao, Chunjie, Gao, Xia, Chai, Renjie
Format: Artigo
Langue:Inglês
Publié: Springer International Publishing 2019
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Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113235/
https://ncbi.nlm.nih.gov/pubmed/31485717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-019-03291-2
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