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LIS1 determines cleavage plane positioning by regulating actomyosin-mediated cell membrane contractility
Heterozygous loss of human PAFAH1B1 (coding for LIS1) results in the disruption of neurogenesis and neuronal migration via dysregulation of microtubule (MT) stability and dynein motor function/localization that alters mitotic spindle orientation, chromosomal segregation, and nuclear migration. Recen...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7112955/ https://ncbi.nlm.nih.gov/pubmed/32159512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51512 |
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