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LIS1 determines cleavage plane positioning by regulating actomyosin-mediated cell membrane contractility
Heterozygous loss of human PAFAH1B1 (coding for LIS1) results in the disruption of neurogenesis and neuronal migration via dysregulation of microtubule (MT) stability and dynein motor function/localization that alters mitotic spindle orientation, chromosomal segregation, and nuclear migration. Recen...
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| Yayımlandı: | eLife |
|---|---|
| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
eLife Sciences Publications, Ltd
2020
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7112955/ https://ncbi.nlm.nih.gov/pubmed/32159512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.51512 |
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