Safety and immunogenicity of mammalian cell derived and Modified Vaccinia Ankara vectored African swine fever subunit antigens in swine

A reverse vaccinology system, Vaxign, was used to identify and select a subset of five African Swine Fever (ASF) antigens that were successfully purified from human embryonic kidney 293 (HEK) cells and produced in Modified vaccinia virus Ankara (MVA) viral vectors. Three HEK-purified antigens [B646L...

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Udgivet i:Vet Immunol Immunopathol
Main Authors: Lopera-Madrid, Jaime, Osorio, Jorge E., He, Yongqun, Xiang, Zuoshuang, Adams, L. Garry, Laughlin, Richard C., Mwangi, Waithaka, Subramanya, Sandesh, Neilan, John, Brake, David, Burrage, Thomas G., Brown, William Clay, Clavijo, Alfonso, Bounpheng, Mangkey A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier B.V. 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112906/
https://ncbi.nlm.nih.gov/pubmed/28241999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vetimm.2017.01.004
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