Endoribonuclease activities of porcine reproductive and respiratory syndrome virus nsp11 was essential for nsp11 to inhibit IFN-β induction

Previous studies have shown that PRRSV nsp11, which was an endoribonuclease, was an interferon antagonist, however, the mechanism that nsp11 inhibited IFN-β production was unclear. To explore whether the endoribonuclease was required for nsp11 to disrupt the IFN-β production, substitutions of the pr...

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Bibliographic Details
Published in:Mol Immunol
Main Authors: Shi, Xibao, Wang, Li, Li, Xuewu, Zhang, Gaiping, Guo, Junqing, Zhao, Dong, Chai, Shujun, Deng, Ruiguang
Format: Artigo
Language:Inglês
Published: Elsevier Ltd. 2011
Subjects:
Short Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112683/
https://ncbi.nlm.nih.gov/pubmed/21481939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2011.03.004
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