A Dimerization-Dependent Mechanism Drives the Endoribonuclease Function of Porcine Reproductive and Respiratory Syndrome Virus nsp11

Porcine reproductive and respiratory syndrome virus (PRRSV) RNA endoribonuclease nsp11 belongs to the XendoU superfamily and plays a crucial role in arterivirus replication. Here, we report the first crystal structure of the arterivirus nsp11 protein from PRRSV, which exhibits a unique structure and...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Shi, Yuejun, Li, Youwen, Lei, Yingying, Ye, Gang, Shen, Zhou, Sun, Limeng, Luo, Rui, Wang, Dang, Fu, Zhen F., Xiao, Shaobo, Peng, Guiqing
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2016
Soggetti:
Structure and Assembly
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836315/
https://ncbi.nlm.nih.gov/pubmed/26912626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03065-15
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