A Dimerization-Dependent Mechanism Drives the Endoribonuclease Function of Porcine Reproductive and Respiratory Syndrome Virus nsp11

Porcine reproductive and respiratory syndrome virus (PRRSV) RNA endoribonuclease nsp11 belongs to the XendoU superfamily and plays a crucial role in arterivirus replication. Here, we report the first crystal structure of the arterivirus nsp11 protein from PRRSV, which exhibits a unique structure and...

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Publicado en:J Virol
Autores principales: Shi, Yuejun, Li, Youwen, Lei, Yingying, Ye, Gang, Shen, Zhou, Sun, Limeng, Luo, Rui, Wang, Dang, Fu, Zhen F., Xiao, Shaobo, Peng, Guiqing
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
Materias:
Structure and Assembly
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836315/
https://ncbi.nlm.nih.gov/pubmed/26912626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03065-15
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