A Dimerization-Dependent Mechanism Drives the Endoribonuclease Function of Porcine Reproductive and Respiratory Syndrome Virus nsp11

Porcine reproductive and respiratory syndrome virus (PRRSV) RNA endoribonuclease nsp11 belongs to the XendoU superfamily and plays a crucial role in arterivirus replication. Here, we report the first crystal structure of the arterivirus nsp11 protein from PRRSV, which exhibits a unique structure and...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Shi, Yuejun, Li, Youwen, Lei, Yingying, Ye, Gang, Shen, Zhou, Sun, Limeng, Luo, Rui, Wang, Dang, Fu, Zhen F., Xiao, Shaobo, Peng, Guiqing
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2016
Предметы:
Structure and Assembly
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4836315/
https://ncbi.nlm.nih.gov/pubmed/26912626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03065-15
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