Cytokines and synthetic double-stranded RNA augment the T helper 1 immune response of swine to porcine reproductive and respiratory syndrome virus

Immunization of pigs with a modified live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine initially elicits a weak interferon (IFN)-γ response. To improve the immune response, an adjuvant consisting of plasmid encoding either porcine interleukin (IL)-12 or IFN-α was co-administer...

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Detalhes bibliográficos
Publicado no:Vet Immunol Immunopathol
Main Authors: Meier, William A., Husmann, Robert J., Schnitzlein, William M., Osorio, Fernando A., Lunney, Joan K., Zuckermann, Federico A.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112576/
https://ncbi.nlm.nih.gov/pubmed/15507313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vetimm.2004.09.012
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